Phosphodiesterase Type 5 Inhibitor Sildenafil Decreases the Proinflammatory Chemokine CXCL10 in Human Cardiomyocytes and in Subjects with Diabetic Cardiomyopathy

T helper 1 (Th1) type cytokines and chemokines are bioactive mediators in inflammation underling several diseases and co-morbid conditions, such as cardiovascular and metabolic disorders. Th1 chemokine CXCL10 participates in heart damage initiation/progression; cardioprotection has been recently ass...

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Detalhes bibliográficos
Publicado no:Inflammation
Main Authors: Di Luigi, Luigi, Corinaldesi, Clarissa, Colletti, Marta, Scolletta, Sabino, Antinozzi, Cristina, Vannelli, Gabriella B., Giannetta, Elisa, Gianfrilli, Daniele, Isidori, Andrea M., Migliaccio, Silvia, Poerio, Noemi, Fraziano, Maurizio, Lenzi, Andrea, Crescioli, Clara
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4883282/
https://ncbi.nlm.nih.gov/pubmed/27165639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10753-016-0359-6
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