Subthreshold nitric oxide synthase inhibition improves synergistic effects of subthreshold MMP‐2/MLCK‐mediated cardiomyocyte protection from hypoxic injury

Injury of myocardium during ischaemia/reperfusion (I/R) is a complex and multifactorial process involving uncontrolled protein phosphorylation, nitration/nitrosylation by increased production of nitric oxide and accelerated contractile protein degradation by matrix metalloproteinase‐2 (MMP‐2). It ha...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cell Mol Med
Main Authors: Bil‐Lula, Iwona, Lin, Han‐Bin, Biały, Dariusz, Wawrzyńska, Magdalena, Diebel, Lucas, Sawicka, Jolanta, Woźniak, Mieczyslaw, Sawicki, Grzegorz
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882990/
https://ncbi.nlm.nih.gov/pubmed/26992120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12827
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