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Lysosomal cholesterol accumulation in macrophages leading to coronary atherosclerosis in CD38(−/−) mice

The disruption in transportation of oxLDL‐derived cholesterol and the subsequent lipid accumulation in macrophages are the hallmark events in atherogenesis. Our recent studies demonstrated that lysosomal Ca(2+) messenger of nicotinic acid adenine dinucleotide phosphate (NAADP), an enzymatic product...

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Bibliografske podrobnosti
izdano v:J Cell Mol Med
Main Authors: Xu, Xiaoyang, Yuan, Xinxu, Li, Ningjun, Dewey, William L., Li, Pin‐Lan, Zhang, Fan
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882979/
https://ncbi.nlm.nih.gov/pubmed/26818887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12788
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