Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor

BACKGROUND: Perturbed genotypes in cancer can now be identified by whole genome sequencing of large number of diverse tumor samples, and observed gene mutations can be used for prognosis and classification of cancer subtypes. Although mutations in a few causative genes are directly linked to key sig...

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Publicat a:BMC Cancer
Autors principals: Daakour, Sarah, Hajingabo, Leon Juvenal, Kerselidou, Despoina, Devresse, Aurelie, Kettmann, Richard, Simonis, Nicolas, Dequiedt, Franck, Twizere, Jean-Claude
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882867/
https://ncbi.nlm.nih.gov/pubmed/27229929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2374-2
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