DNA methylation analysis of paediatric low-grade astrocytomas identifies a tumour-specific hypomethylation signature in pilocytic astrocytomas

Low-grade gliomas (LGGs) account for about a third of all brain tumours in children. We conducted a detailed study of DNA methylation and gene expression to improve our understanding of the biology of pilocytic and diffuse astrocytomas. Pilocytic astrocytomas were found to have a distinctive signatu...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Acta Neuropathol Commun
Autors principals: Jeyapalan, Jennie N., Doctor, Gabriel T., Jones, Tania A., Alberman, Samuel N., Tep, Alexander, Haria, Chirag M., Schwalbe, Edward C., Morley, Isabel C. F., Hill, Alfred A., LeCain, Magdalena, Ottaviani, Diego, Clifford, Steven C., Qaddoumi, Ibrahim, Tatevossian, Ruth G., Ellison, David W., Sheer, Denise
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882864/
https://ncbi.nlm.nih.gov/pubmed/27229157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0323-6
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars