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Sustained efficacy of artesunate-sulfadoxine-pyrimethamine against Plasmodium falciparum in Yemen and a renewed call for an adjunct single dose primaquine to clear gametocytes

BACKGROUND: In Yemen, artesunate plus sulfadoxine-pyrimethamine (AS + SP) has been used as first-line treatment for uncomplicated falciparum malaria, which accounts for about 99 % of malaria cases. There is evidence that resistance to SP is increasing, with potential negative impact on efficacy, and...

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Détails bibliographiques
Publié dans:Malar J
Auteurs principaux: Atroosh, Wahib M., Al-Mekhlafi, Hesham M., Snounou, Georges, Al-Jasari, Adel, Sady, Hany, Nasr, Nabil A., Lau, Yee-Ling, Surin, Johari
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882835/
https://ncbi.nlm.nih.gov/pubmed/27234587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1344-0
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