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The germinal center antibody response in health and disease

The germinal center response is the delayed but sustained phase of the antibody response that is responsible for producing high-affinity antibodies of the IgG, IgA and/or IgE isotypes. B cells in the germinal center undergo re-iterative cycles of somatic hypermutation of immunoglobulin gene variable...

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Bibliographic Details
Published in:F1000Res
Main Author: DeFranco, Anthony L.
Format: Artigo
Language:Inglês
Published: F1000Research 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882753/
https://ncbi.nlm.nih.gov/pubmed/27303636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.7717.1
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