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Toll-like receptor 9 signaling acts on multiple elements of the germinal center to enhance antibody responses

Recent studies have demonstrated important roles of nucleic acid-sensing Toll-like receptors (TLRs) in promoting protective antibody responses against several viruses. To dissect how recognition of nucleic acids by TLRs enhances germinal center (GC) responses, mice selectively deleted for myeloid di...

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Autori principali: Rookhuizen, Derek C., DeFranco, Anthony L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128120/
https://ncbi.nlm.nih.gov/pubmed/25053813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323985111
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