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Isolation and Reactivity of Trifluoromethyl Iodonium Salts

[Image: see text] The strategic incorporation of the trifluoromethyl (CF(3)) functionality within therapeutic or agrochemical agents is a proven strategy for altering their associated physicochemical properties (e.g., metabolic stability, lipophilicity, and bioavailability). Electrophilic trifluorom...

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Publicat a:ACS Cent Sci
Autors principals: Brantley, Johnathan N., Samant, Andrew V., Toste, F. Dean
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2016
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882740/
https://ncbi.nlm.nih.gov/pubmed/27280169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.6b00119
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