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Interaction of a novel fluorescent GTP analogue with the small G-protein K-Ras
A novel fluorescent guanosine 5′-triphosphate (GTP) analogue, 2′(3′)-O-{6-(N-(7-nitrobenz-2-oxa-l,3-diazol-4-yl)amino) hexanoic}-GTP (NBD-GTP), was synthesized and utilized to monitor the effect of mutations in the functional region of mouse K-Ras. The effects of the G12S, A59T and G12S/A59T mutatio...
Guardat en:
| Publicat a: | J Biochem |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4882638/ https://ncbi.nlm.nih.gov/pubmed/26184075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvv071 |
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