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Effect of CLU genetic variants on cerebrospinal fluid and neuroimaging markers in healthy, mild cognitive impairment and Alzheimer’s disease cohorts

The Clusterin (CLU) gene, also known as apolipoprotein J (ApoJ), is currently the third most associated late-onset Alzheimer’s disease (LOAD) risk gene. However, little was known about the possible effect of CLU genetic variants on AD pathology in brain. Here, we evaluated the interaction between 7...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tan, Lin, Wang, Hui-Fu, Tan, Meng-Shan, Tan, Chen-Chen, Zhu, Xi-Chen, Miao, Dan, Yu, Wan-Jiang, Jiang, Teng, Tan, Lan, Yu, Jin-Tai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882617/
https://ncbi.nlm.nih.gov/pubmed/27229352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26027
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