Major Histocompatibility Complex class I proteins are critical for maintaining neuronal structural complexity in the aging brain

Major histocompatibility complex class I (MHCI) proteins have been implicated in neuronal function through the modulation of neuritogenesis, synaptogenesis, synaptic plasticity, and memory consolidation during development. However, the involvement of MHCI in the aged brain is unclear. Here we demons...

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Pubblicato in:Sci Rep
Autori principali: Lazarczyk, Maciej J., Kemmler, Julia E., Eyford, Brett A., Short, Jennifer A., Varghese, Merina, Sowa, Allison, Dickstein, Daniel R., Yuk, Frank J., Puri, Rishi, Biron, Kaan E., Leist, Marcel, Jefferies, Wilfred A., Dickstein, Dara L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882527/
https://ncbi.nlm.nih.gov/pubmed/27229916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26199
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