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Amylin structure–function relationships and receptor pharmacology: implications for amylin mimetic drug development

Amylin is an important, but poorly understood, 37 amino acid glucoregulatory hormone with great potential to target metabolic diseases. A working example that the amylin system is one worth developing is the FDA‐approved drug used in insulin‐requiring diabetic patients, pramlintide. However, certain...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Bower, Rebekah L, Hay, Debbie L
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882495/
https://ncbi.nlm.nih.gov/pubmed/27061187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13496
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