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DNA Polymerase III, but Not Polymerase IV, Must Be Bound to a τ-Containing DnaX Complex to Enable Exchange into Replication Forks

Examples of dynamic polymerase exchange have been previously characterized in model systems provided by coliphages T4 and T7. Using a dominant negative D403E polymerase (Pol) III α that can form initiation complexes and sequester primer termini but not elongate, we investigated the possibility of ex...

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Vydáno v:J Biol Chem
Hlavní autoři: Yuan, Quan, Dohrmann, Paul R., Sutton, Mark D., McHenry, Charles S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882441/
https://ncbi.nlm.nih.gov/pubmed/27056333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.725358
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