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Effects of Subretinal Gene Transfer at Different Time Points in a Mouse Model of Retinal Degeneration
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) is necessary for photoreceptors to generate an important lipid component of their membranes. The absence of LPCAT1 results in early and rapid rod and cone degeneration. Retinal degeneration 11 (rd11) mice carry a mutation in the Lpcat1 gene, and are...
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| Publicado en: | PLoS One |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4882044/ https://ncbi.nlm.nih.gov/pubmed/27228218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156542 |
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