Trans-Corneal Subretinal Injection in Mice and Its Effect on the Function and Morphology of the Retina

PURPOSE: To introduce a practical method of subretinal injection in mice and evaluate injection-induced retinal detachment (RD) and damage using a dynamic imaging system, electrophysiology, and histology. METHODS: After full dilation of a 2-month-old C57BL/6J mouse pupil, the cornea near the limbus...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Qi, Yan, Dai, Xufeng, Zhang, Hua, He, Ying, Zhang, Yangyang, Han, Juanjuan, Zhu, Ping, Zhang, Yuxin, Zheng, Qinxiang, Li, Xia, Zhao, Chen, Pang, Jijing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552822/
https://ncbi.nlm.nih.gov/pubmed/26317758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136523
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