MRI Based Localisation and Quantification of Abscesses following Experimental S. aureus Intravenous Challenge: Application to Vaccine Evaluation

PURPOSE: To develop and validate a sensitive and specific method of abscess enumeration and quantification in a preclinical model of Staphylococcus aureus infection. METHODS: S. aureus infected murine kidneys were fixed in paraformaldehyde, impregnated with gadolinium, and embedded in agar blocks, w...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Allen, Elizabeth R., van Diemen, Pauline, Yamaguchi, Yuko, Lindemann, Claudia, Soilleux, Elizabeth, Rollier, Christine, Hill, Fergal, Schneider, Jurgen, Wyllie, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881890/
https://ncbi.nlm.nih.gov/pubmed/27228181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154705
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