Spatial Colocalization and Functional Link of Purinosomes with Mitochondria

Purine biosynthetic enzymes organize into dynamic cellular bodies called purinosomes. Little is known about the spatiotemporal control of these structures. Using super-resolution microscopy, we demonstrated that purinosomes colocalized with mitochondria, and these results were supported by isolation...

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Veröffentlicht in:Science
Hauptverfasser: French, Jarrod B., Jones, Sara A., Deng, Huayun, Pedley, Anthony M., Kim, Doory, Chan, Chung Yu, Hu, Haibei, Pugh, Raymond J., Zhao, Hong, Zhang, Youxin, Huang, Tony Jun, Fang, Ye, Zhuang, Xiaowei, Benkovic, Stephen J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881839/
https://ncbi.nlm.nih.gov/pubmed/26912862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aac6054
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