Acute Ozone-Induced Pulmonary and Systemic Metabolic Effects Are Diminished in Adrenalectomized Rats

Acute ozone exposure increases circulating stress hormones and induces metabolic alterations in animals. We hypothesized that the increase of adrenal-derived stress hormones is necessary for both ozone-induced metabolic effects and lung injury. Male Wistar-Kyoto rats underwent bilateral adrenal deme...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Miller, Desinia B., Snow, Samantha J., Schladweiler, Mette C., Richards, Judy E., Ghio, Andrew J., Ledbetter, Allen D., Kodavanti, Urmila P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Adrenal Gland Function and Pulmonary Response to Ozone
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881831/
https://ncbi.nlm.nih.gov/pubmed/26732886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv331
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