Chop Deficiency Protects Mice Against Bleomycin-induced Pulmonary Fibrosis by Attenuating M2 Macrophage Production

C/EBP homologous protein (Chop) has been shown to have altered expression in patients with idiopathic pulmonary fibrosis (IPF), but its exact role in IPF pathoaetiology has not been fully addressed. Studies conducted in patients with IPF and Chop(−/−) mice have dissected the role of Chop and endopla...

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Vydáno v:Mol Ther
Hlavní autoři: Yao, Yingying, Wang, Yi, Zhang, Zhijun, He, Long, Zhu, Jianghui, Zhang, Meng, He, Xiaoyu, Cheng, Zhenshun, Ao, Qilin, Cao, Yong, Yang, Ping, Su, Yunchao, Zhao, Jianping, Zhang, Shu, Yu, Qilin, Ning, Qin, Xiang, Xudong, Xiong, Weining, Wang, Cong-Yi, Xu, Yongjian
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881771/
https://ncbi.nlm.nih.gov/pubmed/26883801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.36
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