Variability in Immunohistochemical Detection of Programmed Death Ligand 1 (PD-L1) in Cancer Tissue Types

In normal cell physiology, programmed death 1 (PD-1) and its ligand, PD-L1, play an immunoregulatory role in T-cell activation, tolerance, and immune-mediated tissue damage. The PD-1/PD-L1 pathway also plays a critical role in immune escape of tumor cells and has been demonstrated to correlate with...

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Udgivet i:Int J Mol Sci
Main Authors: Scognamiglio, Giosuè, De Chiara, Anna, Di Bonito, Maurizio, Tatangelo, Fabiana, Losito, Nunzia Simona, Anniciello, Annamaria, De Cecio, Rossella, D’Alterio, Crescenzo, Scala, Stefania, Cantile, Monica, Botti, Gerardo
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881606/
https://ncbi.nlm.nih.gov/pubmed/27213372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17050790
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