Fanconi anemia proteins function in mitophagy and immunity

Fanconi anemia (FA) pathway genes are important tumor suppressors whose best-characterized function is repair of damaged nuclear DNA. Herein, we describe an essential role for FA genes in two forms of selective autophagy. Genetic deletion of Fancc blocks the autophagic clearance of viruses (virophag...

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Detaylı Bibliyografya
Yayımlandı:Cell
Asıl Yazarlar: Sumpter, Rhea, Sirasanagandla, Shyam, Fernández, Álvaro F., Wei, Yongjie, Dong, Xiaonan, Franco, Luis, Zou, Zhongju, Marchal, Christophe, Lee, Ming Yeh, Clapp, D. Wade, Hanenberg, Helmut, Levine, Beth
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881391/
https://ncbi.nlm.nih.gov/pubmed/27133164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.04.006
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