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Fanconi anemia proteins function in mitophagy and immunity

Fanconi anemia (FA) pathway genes are important tumor suppressors whose best-characterized function is repair of damaged nuclear DNA. Herein, we describe an essential role for FA genes in two forms of selective autophagy. Genetic deletion of Fancc blocks the autophagic clearance of viruses (virophag...

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Bibliografiske detaljer
Udgivet i:Cell
Main Authors: Sumpter, Rhea, Sirasanagandla, Shyam, Fernández, Álvaro F., Wei, Yongjie, Dong, Xiaonan, Franco, Luis, Zou, Zhongju, Marchal, Christophe, Lee, Ming Yeh, Clapp, D. Wade, Hanenberg, Helmut, Levine, Beth
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881391/
https://ncbi.nlm.nih.gov/pubmed/27133164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.04.006
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