Controlled Release of Collagen-Binding SDF-1α Improves Cardiac Function after Myocardial Infarction by Recruiting Endogenous Stem Cells

Stromal cell-derived factor-1α (SDF-1α) is a well-characterized chemokine that mobilizes stem cells homing to the ischemic heart, which is beneficial for cardiac regeneration. However, clinically administered native SDF-1α diffuses quickly, thus decreasing its local concentration, and results in sid...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Sun, Jie, Zhao, Yannan, Li, Qingguo, Chen, Bing, Hou, Xianglin, Xiao, Zhifeng, Dai, Jianwu
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881239/
https://ncbi.nlm.nih.gov/pubmed/27226084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26683
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