Chronic AMD3100 Antagonism of SDF-1α-CXCR4 Exacerbates Cardiac Dysfunction and Remodeling after Myocardial Infarction

The role of the SDF-1α-CXCR4 axis in response to myocardial infarction is unknown. We addressed it using the CXCR4 antagonist, AMD3100, to block SDF-1α interaction with CXCR4 after chronic coronary artery ligation. Chronic AMD3100 treatment decreased ejection fraction and fractional shortening in mi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Dai, Shujing, Yuan, Fangping, Mu, Jingyao, Li, Chengxin, Chen, Ning, Guo, Shangzhi, Kingery, Justin, Prabhu, Sumanth D., Bolli, Roberto, Rokosh, Gregg
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005152/
https://ncbi.nlm.nih.gov/pubmed/20655922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.07.010
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge