Long-Term Administration of AMD3100, an Antagonist of SDF-1/CXCR4 Signaling, Alters Fracture Repair

Fracture healing involves rapid stem and progenitor cell migration, homing, and differentiation. SDF-1 (CXCL12) is considered a master regulator of CXCR4-positive stem and progenitor cell trafficking to sites of ischemic (hypoxic) injury and regulates their subsequent differentiation into mature rep...

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Bibliografiske detaljer
Main Authors: Toupadakis, Chrisoula A., Wong, Alice, Genetos, Damian C., Chung, Dai-Jung, Murugesh, Deepa, Anderson, Matthew J., Loots, Gabriela G., Christiansen, Blaine A., Kapatkin, Amy S., Yellowley, Clare E.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704138/
https://ncbi.nlm.nih.gov/pubmed/22592891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22145
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