SALM5 trans-synaptically interacts with LAR-RPTPs in a splicing-dependent manner to regulate synapse development

Synaptogenic adhesion molecules play critical roles in synapse formation. SALM5/Lrfn5, a SALM/Lrfn family adhesion molecule implicated in autism spectrum disorders (ASDs) and schizophrenia, induces presynaptic differentiation in contacting axons, but its presynaptic ligand remains unknown. We found...

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Published in:Sci Rep
Main Authors: Choi, Yeonsoo, Nam, Jungyong, Whitcomb, Daniel J., Song, Yoo Sung, Kim, Doyoun, Jeon, Sangmin, Um, Ji Won, Lee, Seong-Gyu, Woo, Jooyeon, Kwon, Seok-Kyu, Li, Yan, Mah, Won, Kim, Ho Min, Ko, Jaewon, Cho, Kwangwook, Kim, Eunjoon
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881023/
https://ncbi.nlm.nih.gov/pubmed/27225731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26676
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