SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3–LAR adhesion

Synaptic adhesion molecules regulate various aspects of synapse development, function and plasticity. These functions mainly involve trans-synaptic interactions and positive regulations, whereas cis-interactions and negative regulation are less understood. Here we report that SALM4, a member of the...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Lie, Eunkyung, Ko, Ji Seung, Choi, Su-Yeon, Roh, Junyeop Daniel, Cho, Yi Sul, Noh, Ran, Kim, Doyoun, Li, Yan, Kang, Hyeyeon, Choi, Tae-Yong, Nam, Jungyong, Mah, Won, Lee, Dongmin, Lee, Seong-Gyu, Kim, Ho Min, Kim, Hyun, Choi, Se-Young, Um, Ji Won, Kang, Myoung-Goo, Bae, Yong Chul, Ko, Jaewon, Kim, Eunjoon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974644/
https://ncbi.nlm.nih.gov/pubmed/27480238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12328
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