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Coordinated synthesis and degradation of cdc2 in the mammalian cell cycle.

The product of the cdc2 gene (cdc2 or p34cdc2), the catalytic subunit of M phase-promoting factor (MPF), is held at a constant steady-state level throughout the cell cycle. In this report, we show that the constant concentration is maintained by a coordinated regulation of protein synthesis and degr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Welch, P J, Wang, J Y
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48810/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1372997/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.3093
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