NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?

Several evidences suggest that NK cells can patrol the body and eliminate tumors in their initial phases but may hardly control established solid tumors. Multiple factors, including the transition of tumor cells towards a proinvasive/prometastatic phenotype, the immunosuppressive effect of the tumor...

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Vydáno v:J Immunol Res
Hlavní autoři: Cantoni, Claudia, Huergo-Zapico, Leticia, Parodi, Monica, Pedrazzi, Marco, Mingari, Maria Cristina, Moretta, Alessandro, Sparatore, Bianca, Gonzalez, Segundo, Olive, Daniel, Bottino, Cristina, Castriconi, Roberta, Vitale, Massimo
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
Témata:
Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880686/
https://ncbi.nlm.nih.gov/pubmed/27294158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4684268
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