NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?

Several evidences suggest that NK cells can patrol the body and eliminate tumors in their initial phases but may hardly control established solid tumors. Multiple factors, including the transition of tumor cells towards a proinvasive/prometastatic phenotype, the immunosuppressive effect of the tumor...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Cantoni, Claudia, Huergo-Zapico, Leticia, Parodi, Monica, Pedrazzi, Marco, Mingari, Maria Cristina, Moretta, Alessandro, Sparatore, Bianca, Gonzalez, Segundo, Olive, Daniel, Bottino, Cristina, Castriconi, Roberta, Vitale, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880686/
https://ncbi.nlm.nih.gov/pubmed/27294158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4684268
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