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How melanoma cells inactivate NK cells

NK cells are the most potent effectors against different tumors in vitro. However, their efficacy in vivo is compromised by suppressive signals delivered by tumor or tumor-associated cells. This study unravels the molecular mechanisms by which melanomas disarm NK cells and offers clues to revert suc...

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Detalhes bibliográficos
Main Authors: Pietra, Gabriella, Vitale, Massimo, Moretta, Lorenzo, Mingari, Maria Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489764/
https://ncbi.nlm.nih.gov/pubmed/23162776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20405
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