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Design of pH-Responsive Biomaterials to Enable the Oral Route of Hematological Factor IX

The oral administration of hematological factor IX can offer a convenient prophylactic treatment for hemophilia B patients. pH-Responsive hydrogels based on poly(methacrylic acid)-grafted-poly(ethylene glycol) (P(MAA-g-EG)) have been engineered as delivery vehicles for factor IX. In oral delivery, s...

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Detalhes bibliográficos
Publicado no:Ann Biomed Eng
Main Authors: Horava, Sarena D., Peppas, Nicholas A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880530/
https://ncbi.nlm.nih.gov/pubmed/26883955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-016-1566-x
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