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Characterization of pH-Responsive Hydrogels of Poly(Itaconic acid-g-Ethylene Glycol) Prepared by UV-Initiated Free Radical Polymerization as Biomaterials for Oral Delivery of Bioactive Agents

Effective oral delivery of proteins is impeded by steep pH gradients and proteolytic enzymes in the gastrointestinal tract, as well as low absorption of the proteins into the bloodstream due to their size, charge or solubility. In the present work, pH-responsive complexation hydrogels of poly(itacon...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Betancourt, Tania, Pardo, Juan, Soo, Ken, Peppas, Nicholas A.
التنسيق: Artigo
اللغة:Inglês
منشور في: 2010
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826507/
https://ncbi.nlm.nih.gov/pubmed/19536838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.32510
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