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Lipocalin 2 Alleviates Iron Toxicity by Facilitating Hypoferremia of Inflammation and Limiting Catalytic Iron Generation

Iron is an essential transition metal ion for virtually all aerobic organisms, yet its dysregulation (iron overload or anemia) is a harbinger of many pathologic conditions. Hence, iron homeostasis is tightly regulated to prevent the generation of catalytic iron (CI) which can damage cellular biomole...

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Detalhes bibliográficos
Publicado no:Biometals
Main Authors: Xiao, Xia, Yeoh, Beng San, Saha, Piu, Olvera, Rodrigo Aguilera, Singh, Vishal, Vijay-Kumar, Matam
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880510/
https://ncbi.nlm.nih.gov/pubmed/27007712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10534-016-9925-5
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