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Lipocalin 2 Alleviates Iron Toxicity by Facilitating Hypoferremia of Inflammation and Limiting Catalytic Iron Generation

Iron is an essential transition metal ion for virtually all aerobic organisms, yet its dysregulation (iron overload or anemia) is a harbinger of many pathologic conditions. Hence, iron homeostasis is tightly regulated to prevent the generation of catalytic iron (CI) which can damage cellular biomole...

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Vydáno v:Biometals
Hlavní autoři: Xiao, Xia, Yeoh, Beng San, Saha, Piu, Olvera, Rodrigo Aguilera, Singh, Vishal, Vijay-Kumar, Matam
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880510/
https://ncbi.nlm.nih.gov/pubmed/27007712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10534-016-9925-5
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