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Vitamin D3 Inhibits Wnt/β-Catenin and mTOR Signaling Pathways in Human Uterine Fibroid Cells

CONTEXT: Somatic mutations in the Med12 gene are known to activate Wnt/β-catenin signaling in human uterine fibroids (UFs). OBJECTIVE: The objective of the study was to examine the role of vitamin D3 in the modulation of Wnt/β-catenin and mammalian target of rapamycin (mTOR) signaling in human UF ce...

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Bibliografski detalji
Izdano u:J Clin Endocrinol Metab
Glavni autori: Al-Hendy, Ayman, Diamond, Michael P., Boyer, Thomas G., Halder, Sunil K.
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880168/
https://ncbi.nlm.nih.gov/pubmed/26820714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2015-3555
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