Identification of Environmental Quaternary Ammonium Compounds as Direct Inhibitors of Cholesterol Biosynthesis

In this study, we aim to identify environmental molecules that can inhibit cholesterol biosynthesis, potentially leading to the same biochemical defects as observed in cholesterol biosynthesis disorders, which are often characterized by congenital malformations and developmental delay. Using the Dis...

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Bibliografski detalji
Izdano u:Toxicol Sci
Glavni autori: Herron, Josi, Reese, Rosalyn C., Tallman, Keri A., Narayanaswamy, Rohini, Porter, Ned A., Xu, Libin
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Identification of Cholesterol Biosynthesis Inhibitors
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880132/
https://ncbi.nlm.nih.gov/pubmed/26919959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw041
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