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β-Cell Deficit in Obese Type 2 Diabetes, a Minor Role of β-Cell Dedifferentiation and Degranulation
CONTEXT: Type 2 diabetes is characterized by a β-cell deficit and a progressive defect in β-cell function. It has been proposed that the deficit in β-cells may be due to β-cell degranulation and transdifferentiation to other endocrine cell types. OBJECTIVE: The objective of the study was to establis...
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| 發表在: | J Clin Endocrinol Metab |
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| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Endocrine Society
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4880126/ https://ncbi.nlm.nih.gov/pubmed/26700560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2015-3566 |
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