Increased Frequency of Hormone Negative and Polyhormonal Endocrine Cells in Lean Individuals With Type 2 Diabetes

CONTEXT: It has been suggested that beta cell loss in type 2 diabetes (T2D) may be due to beta cell degranulation and/or altered cell identity. While shown to have a minor role in obese T2D, this has not been evaluated in lean T2D. OBJECTIVE: To establish the contribution of altered beta cell identi...

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Bibliografske podrobnosti
izdano v:J Clin Endocrinol Metab
Main Authors: Saleh Md Moin, Abu, Dhawan, Sangeeta, Cory, Megan, Butler, Peter C., Rizza, Robert A., Butler, Alexandra E.
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2016
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052343/
https://ncbi.nlm.nih.gov/pubmed/27472443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-2496
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