Shedding light on betL*: pPL2-lux mediated real-time analysis of betL* expression in Listeria monocytogenes

We propose a mechanism of action for the betL* mutation which is based on DNA topology. Removing a single thymine residue from the betL σ(A) promoter's −10 and −35 spacer results in a ‘twist’-mediated activation of transcription which accounts for the osmotolerance phenotype observed for strain...

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Veröffentlicht in:Bioengineered
Hauptverfasser: Keane, Shauna M., Culligan, Eamonn P., Hoffmann, Roland F., Gahan, Cormac G.M., Hill, Colin, Snelling, William J., Sleator, Roy D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879987/
https://ncbi.nlm.nih.gov/pubmed/27212260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21655979.2016.1171438
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