Neuroprotective effects of the immunomodulatory drug FK506 in a model of HIV1-gp120 neurotoxicity

BACKGROUND: HIV-associated neurocognitive disorders (HAND) continue to be a common morbidity associated with chronic HIV infection. It has been shown that HIV proteins (e.g., gp120) released from infected microglial/macrophage cells can cause neuronal damage by triggering inflammation and oxidative...

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Veröffentlicht in:J Neuroinflammation
Hauptverfasser: Fields, Jerel A., Overk, Cassia, Adame, Anthony, Florio, Jazmin, Mante, Michael, Pineda, Andrea, Desplats, Paula, Rockenstein, Edward, Achim, Cristian, Masliah, Eliezer
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879748/
https://ncbi.nlm.nih.gov/pubmed/27220536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0585-8
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