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DNA damage and mutation in human cells exposed to nitric oxide in vitro.

Nitric oxide (NO.) is a physiological messenger formed by several cell types. Reaction with O2 forms oxides that nitrosate amines at pH values near 7. We now report experiments in which NO. was added to intact human cells and to aerobic solutions of DNA, RNA, guanine, or adenine. TK6 human lymphobla...

Täydet tiedot

Tallennettuna:
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Nguyen, T, Brunson, D, Crespi, C L, Penman, B W, Wishnok, J S, Tannenbaum, S R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1992
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48797/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1557408/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.3030
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