DNA damage and mutation in human cells exposed to nitric oxide in vitro.

Nitric oxide (NO.) is a physiological messenger formed by several cell types. Reaction with O2 forms oxides that nitrosate amines at pH values near 7. We now report experiments in which NO. was added to intact human cells and to aerobic solutions of DNA, RNA, guanine, or adenine. TK6 human lymphobla...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Nguyen, T, Brunson, D, Crespi, C L, Penman, B W, Wishnok, J S, Tannenbaum, S R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48797/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1557408/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.3030
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