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Diabetic Phenotypes and Late Life Dementia Risk: A Mechanism-Specific Mendelian Randomization Study

BACKGROUND: Mendelian Randomization (MR) studies have reported that type 2 diabetes (T2D) was not associated with Alzheimer's Disease (AD). We adopted a modified, mechanism-specific MR design to explore this surprising result. METHODS: Using inverse-variance weighted MR analysis, we evaluated t...

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Bibliografiske detaljer
Udgivet i:Alzheimer Dis Assoc Disord
Main Authors: Walter, Stefan, Marden, Jessica R., Kubzansky, Laura D., Mayeda, Elizabeth Rose, Crane, Paul K., Chang, Shun-Chiao, Cornelis, Marilyn, Rehkopf, David H., Mukherjee, Shubhabrata, Glymour, M. Maria
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879683/
https://ncbi.nlm.nih.gov/pubmed/26650880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WAD.0000000000000128
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