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Evaluating the Effects of Surotomycin Treatment on Clostridium difficile Toxin A and B Production, Immune Response, and Morphological Changes

Surotomycin is a cyclic lipopeptide in development for Clostridium difficile-associated diarrhea. This study aimed to assess the impact of surotomycin exposure on C. difficile toxin A and B concentrations and the associated changes in immune response in comparison to vancomycin and metronidazole. Ti...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Endres, Bradley T., Bassères, Eugénie, Khaleduzzaman, Mohammed, Alam, M. Jahangir, Chesnel, Laurent, Garey, Kevin W.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879405/
https://ncbi.nlm.nih.gov/pubmed/27021314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00211-16
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