Assessing Predictive Performance of Published Population Pharmacokinetic Models of Intravenous Tobramycin in Pediatric Patients

Several population pharmacokinetic models describe the dose-exposure relationship of tobramycin in pediatric patients. Before the implementation of these models in clinical practice for dosage adjustment, their predictive performance should be externally evaluated. This study tested the predictive p...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Bloomfield, Celeste, Staatz, Christine E., Unwin, Sean, Hennig, Stefanie
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879400/
https://ncbi.nlm.nih.gov/pubmed/27001806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02654-15
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