Population Pharmacokinetics of Intravenous and Oral Acyclovir and Oral Valacyclovir in Pediatric Population To Optimize Dosing Regimens

Acyclovir is an antiviral currently used for the prevention and treatment of herpes simplex virus (HSV) and varicella-zoster virus (VZV) infections. This study aimed to characterize the pharmacokinetics (PK) of acyclovir and its oral prodrug valacyclovir to optimize dosing in children. Children rece...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Abdalla, S., Briand, C., Oualha, M., Bendavid, M., Béranger, A., Benaboud, S., Tréluyer, J.-M., Zheng, Y., Capito, C., Demir, Z., Foissac, F., Winter, S., Gana, I., Boujaafar, S., Bouazza, N., Hirt, D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674054/
https://ncbi.nlm.nih.gov/pubmed/32988829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01426-20
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