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Efficacy of Artilysin Art-175 against Resistant and Persistent Acinetobacter baumannii

Bacteriophage-encoded endolysins have shown promise as a novel class of antibacterials with a unique mode of action, i.e., peptidoglycan degradation. However, Gram-negative pathogens are generally not susceptible due to their protective outer membrane. Artilysins overcome this barrier. Artilysins ar...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Defraine, Valerie, Schuermans, Joris, Grymonprez, Barbara, Govers, Sander K., Aertsen, Abram, Fauvart, Maarten, Michiels, Jan, Lavigne, Rob, Briers, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879360/
https://ncbi.nlm.nih.gov/pubmed/27021321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00285-16
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