Art-175 Is a Highly Efficient Antibacterial against Multidrug-Resistant Strains and Persisters of Pseudomonas aeruginosa

Artilysins constitute a novel class of efficient enzyme-based antibacterials. Specifically, they covalently combine a bacteriophage-encoded endolysin, which degrades the peptidoglycan, with a targeting peptide that transports the endolysin through the outer membrane of Gram-negative bacteria. Art-08...

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Detalhes bibliográficos
Main Authors: Briers, Yves, Walmagh, Maarten, Grymonprez, Barbara, Biebl, Manfred, Pirnay, Jean-Paul, Defraine, Valerie, Michiels, Jan, Cenens, William, Aertsen, Abram, Miller, Stefan, Lavigne, Rob
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068523/
https://ncbi.nlm.nih.gov/pubmed/24752267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02668-14
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