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AChRs Are Essential for the Targeting of Rapsyn to the Postsynaptic Membrane of NMJs in Living Mice

Rapsyn, a 43 kDa scaffold protein, is required for the clustering of acetylcholine receptors (AChRs) at synaptic sites between mammalian motor neurons and muscle cells. However, the mechanism by which rapsyn is inserted and retained at postsynaptic sites at the neuromuscular junction (NMJ) in vivo r...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Chen, Po-Ju, Martinez-Pena y Valenzuela, Isabel, Aittaleb, Mohamed, Akaaboune, Mohammed
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879192/
https://ncbi.nlm.nih.gov/pubmed/27225759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4580-15.2016
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