Accessory Factors of Cytoplasmic Viral RNA Sensors Required for Antiviral Innate Immune Response

Type I interferon (IFN) induces many antiviral factors in host cells. RIG-I-like receptors (RLRs) are cytoplasmic viral RNA sensors that trigger the signal to induce the innate immune response that includes type I IFN production. RIG-I and MDA5 are RLRs that form nucleoprotein filaments along viral...

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Vydáno v:Front Immunol
Hlavní autoři: Oshiumi, Hiroyuki, Kouwaki, Takahisa, Seya, Tsukasa
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879126/
https://ncbi.nlm.nih.gov/pubmed/27252702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00200
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